Tag: Larotrectinib

New cancer treatment approved for patients with specifically mutated NTRK-mutated solid tumors

In November 2018, larotrectinib was approved by the FDA for treatment of patients with solid tumors that have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion.  NTRK gene fusions are most commonly seen in salivary gland tumors, soft tissue sarcoma and thyroid cancer.  Larotrectinib is an oral medicine that inhibits proteins encoded by the NTRK… Read more »