Tag: New England Journal of Medicine

Immunotherapy treatment with ipilumimab for high-risk melanoma

Immunotherapy treatment with ipilumimab after resection of high-risk melanoma improves overall survival compared to no treatment. In high risk melanoma lesions where a cutaneous melanoma has spread to local lymph nodes, despite surgical resection, only about 45% of patients will not have the melanoma come back within 4 years. Currently, there are no great medical… Read more »


Palbociclib and hormonal therapy has proven progression-free survival benefit

In hormone-positive metastatic breast cancer, combination therapy with palbociclib and hormonal therapy has proven progression-free survival benefit Palbociclib is an oral drug that inhibits cell cycle growth by blocking cells from initiating initial switch to the growth cycle of cells though CDK4 (Cyclin D-Dependent Kinase) and CDK 6 inhibition. This drug has been found to… Read more »